참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Acetic Anhydride | HCID 7918 | — |
| 반응물 | 2-[4-(Dimethylamino)benzoyl]benzoic acid | HCID 88937 | — |
| 반응물 | 1,3-Benzenediamine, N1,N1,N3,N3-tetramethyl- | HCID 89715 | — |
| 생성물 | 3-(2,4-Bis(dimethylamino)phenyl)-3-(4-(dimethylamino)phenyl)phthalide | HCID 20440832 | — |
반응 단계
A mixture of 2-(4-(dimethylamino)benzoyl)benzoic acid (26.8 g.), N,N,N',N'-tetramethyl-m-phenylenediamine (16.4 g.) and acetic anhydride (80 g.) was heated (to 95° C.) during one hour, cooled and poured into dilute hydrochloric acid. The resulting mixture was basified. Recrystallization of the resulting solid from a mixture of toluene and hexane afforded 3-(2,4-bis(dimethylamino)phenyl)-3-(4-(dimethylamino)-phenyl)phthalide (I: X=Y4 =(CH3)2N, Y2 =Z4 =Z5 =Z6 =Z7 =H) (m.p. 190°-194° C.).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04209618 |
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| 출처 데이터셋 | uspto-grants-1980_06 |
|---|
| ORD ID | ord-4943263f11e249f094588e17f61a020f |
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| 출처 메모 | uspto-grants-1980_06 |
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