Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-[2-(4-Pyridinyl)ethyl]piperazine → 8-Chloro-10,11-dihydro-10-[[4-[2-(4-pyridinyl)ethyl]-1-piperazinyl]carbonyl]dibenz[b,f][1,4]oxazepine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-[2-(4-Pyridinyl)ethyl]piperazine | HCID 558685 | — |
| 반응물 | 8-chlorodibenz[b,f][1,4]oxazepin-10(11H)carbonyl chloride | HCID 14975983 | — |
| 생성물 | 8-Chloro-10,11-dihydro-10-[[4-[2-(4-pyridinyl)ethyl]-1-piperazinyl]carbonyl]dibenz[b,f][1,4]oxazepine | HCID 15224926 | 291.3% |
반응 단계
The title compound of Example 2 (0.38 g, 1.3 mmol) was combined with the product of Example 88 (0.25 g, 1.3 mmol) and the reaction was carried out by the method of Example 4. Following chromatographic separation, 1.7 g of the white solid title product was obtained.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05354747 |
| 출처 데이터셋 | uspto-grants-1994_10 |
| ORD ID | ord-525a2e45e5144ec48c3316b67909b848 |
| 출처 메모 | uspto-grants-1994_10 |