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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 1707724생성일: 2026년 10월 27일

2-Chlorothiophene → Methanone, (5-chloro-2-thienyl)phenyl-

https://huagongshe.com/reaction/1707724

반응식

참여 물질

역할이름HCID투입량
반응물2-ChlorothiopheneHCID 7299—
반응물4-tert-ButylphenolHCID 7393—
반응물Benzoyl chlorideHCID 7412—
생성물Methanone, (5-chloro-2-thienyl)phenyl-HCID 901505—
생성물2-Benzoyl-5-(4-t-butyl-phenoxy)thiopheneHCID 19935313—

반응 단계

2-benzoyl-5-chlorothiophene was synthesized via Friedel-Crafts acylation of benzoyl chloride with 2-chlorothiophene. This was reacted under standard conditions with 4-t-butyl phenol to produce 2-benzoyl-5-(4-t-butyl-phenoxy)thiophene. It was discovered by thin layer chromatography that the displacement of the acyl chlorine proceeds completely with no side reactions. Complete nucleophilic displacement demonstrates that this reaction meets the requirements necessary for high polymer formation via a step growth reaction.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US05354836
출처 데이터셋uspto-grants-1994_10
ORD IDord-c7ebfff87e6041958baf6f44204345a9
출처 메모uspto-grants-1994_10