5-Acetoxyacetamido-3-methylcarbamoyl2,4,6-triiodobenzoyl chloride → N-(2,3-dihydroxypropyl)-5-[2,3-diacetoxypropionylamino)-N'-methyl-2,4,6-triiodoisophthalamide

HRID 1707905노트

반응식

HRID 1707905 반응식
[C:1]([O:4][CH:5]([CH2:25][O:26][C:27](=[O:29])[CH3:28])[C:6]([NH:8]C1C(I)=C(C(=O)NC)C(I)=C(C=1I)C(Cl)=O)=[O:7])(=[O:3])[CH3:2].[OH:30][CH:31]([CH2:57][OH:58])[CH2:32][N:33](NC(=O)C)[C:34](=[O:52])[C:35]1[C:44]([I:45])=[C:43](OC(=O)C)[C:42]([I:50])=[C:37]([C:38]([NH:40][CH3:41])=[O:39])[C:36]=1[I:51].C(OCC(NC1C(I)=C(C(=O)NC)C(I)=C(C=1I)C(Cl)=O)=O)(=O)C>>[OH:30][CH:31]([CH2:57][OH:58])[CH2:32][NH:33][C:34](=[O:52])[C:35]1[C:44]([I:45])=[C:43]([NH:8][C:6](=[O:7])[CH:5]([O:4][C:1](=[O:3])[CH3:2])[CH2:25][O:26][C:27](=[O:29])[CH3:28])[C:42]([I:50])=[C:37]([C:38]([NH:40][CH3:41])=[O:39])[C:36]=1[I:51]

참가 물질

4

반응물 3

HCID 156706225-Acetoxyacetamido-3-methylcarbamoyl2,4,6-triiodobenzoyl chlorideHCID 189602905-(2,3-Diacetoxypropionylamino)-3-methylcarbamoyl-2,4,6-triiodobenzoyl chlorideHCID 86748190N-(2,3-dihydroxypropyl)-5-acetoxy-acetamido-N'-methyl-2,4,6-triiodoisophthalamide

생성물 1

HCID 86748189N-(2,3-dihydroxypropyl)-5-[2,3-diacetoxypropionylamino)-N'-methyl-2,4,6-triiodoisophthalamide

실험 절차

Compound (12) is prepared from compound (11) in the same manner according to the procedure described for the preparation of compound (4) from compound (3) in Example I, C.

출처 및 근거

ORD 기록
ord-ac0a11267a894de5a74ba0a74983a8be
출처 데이터셋
uspto-grants-1994_10
특허 번호
US05356613

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