Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium Hydroxide → 2-(4-Toluyl)terephthalic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | [1,1'-Biphenyl]-2,5-dicarboxylic acid, 4'-methyl-, 2,5-dimethyl ester | HCID 105655 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 2-(4-Toluyl)terephthalic acid | HCID 15661445 | 66.2% |
반응 단계
Dimethyl2-(4-tolyl)terephthalate (11.88 g) was suspended in methanol (99 ml). 5M NaOH (50 ml) was added. The reaction mixture was heated at reflux for 1.5 hours. The methanol was removed under reduced pressure. The residue was treated with ethyl acetate and water and the layers separated. The aqueous layer was washed once with ethyl acetate. The aqueous layer was then acidified with 2N HCl and extracted three times with ethyl acetate. These combined organic extracts were then dried over MgSO4, filtered and evaporated under reduced pressure which gave the product (7.09 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05356889 |
| 출처 데이터셋 | uspto-grants-1994_10 |
| ORD ID | ord-7bdac893758244e2ba0ab1b3eb9eee4c |
| 출처 메모 | uspto-grants-1994_10 |