Androsta-5,7-diene-3b,17b-diol → 5alpha-Androst-7-ene-3-one-17beta-ol

반응식

[CH3:1][C@:2]12[CH2:19][CH2:18][C@H:17]3[C:7](=[CH:8][CH:9]=[C:10]4[C@:15]3([CH3:16])[CH2:14][CH2:13][C@H:12]([OH:20])[CH2:11]4)[C@@H:6]1[CH2:5][CH2:4][C@@H:3]2[OH:21].O=C1CC[C@@]2(C)C(CC[C@@H]3[C@@H]2CC[C@@]2(C)[C@H]3CC[C@@H]2CO)=C1>>[CH3:1][C@:2]12[CH2:19][CH2:18][C@H:17]3[C:7](=[CH:8][CH2:9][C@@H:10]4[C@:15]3([CH3:16])[CH2:14][CH2:13][C:12](=[O:20])[CH2:11]4)[C@@H:6]1[CH2:5][CH2:4][C@@H:3]2[OH:21]

참가 물질

반응물 2

HCID 9817420Androsta-5,7-diene-3b,17b-diol

HCID 1437761717beta-Hydroxymethyl-4-androsten-3-on

생성물 1

HCID 186380785alpha-Androst-7-ene-3-one-17beta-ol

실험 절차

The title compound is prepared according to the procedure of Example 4 (i) by substituting androst-4,7-diene-3,17-dione for 3-oxo-17β-(hydroxymethyl)-4androstene.

출처 및 근거

ORD 기록: ord-87d4d913ed0d484e81718978f900151b
출처 데이터셋: uspto-grants-1990_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04946834

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