Sodium Bicarbonate → HCID 178468139, 화합물

HRID 1709195노트

반응식

HRID 1709195 반응식
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][CH2:9][CH2:10][O:11][CH2:12][CH3:13])=[CH:4][CH:3]=1.[NH:14]([C:18]1[CH:26]=[CH:25][C:21]([C:22](Cl)=[O:23])=[CH:20][CH:19]=1)[C:15]([NH2:17])=[NH:16].[C:27]([O-:30])([OH:29])=[O:28].[Na+]>N1C=CC=CC=1>[C:27](=[O:28])([OH:30])[OH:29].[NH:14]([C:18]1[CH:26]=[CH:25][C:21]([C:22]([O:1][C:2]2[CH:3]=[CH:4][C:5]([S:8][CH2:9][CH2:10][O:11][CH2:12][CH3:13])=[CH:6][CH:7]=2)=[O:23])=[CH:20][CH:19]=1)[C:15]([NH2:17])=[NH:16]

참가 물질

5

반응물 3

HCID 516892Sodium BicarbonateHCID 150272734-[(2-Ethoxyethyl)thio]phenolHCID 178512519HCID 178512519, 화합물

생성물 1

HCID 178468139HCID 178468139, 화합물수율 40%

시약·촉매·용매 1

HCID 1049Pyridine용매

실험 절차

3.4 g of 2-ethoxyethyl 4-hydroxyphenyl sulfide was dissolved in 50 ml of pyridine. 4-Guanidinobenzoyl chloride was added to the solution under cooling with ice and the mixture was stirred at room temperature for 27 h. A saturated aqueous solution of sodium hydrocarbonate was added thereto under cooling with ice. A precipitate thus formed was recovered by filtration, washed with water and then with acetone, and dried to obtain 2.86 g (yield: 40 %) of 4-(2-ethoxyethylthio)phenyl 4-guanidinobenzoate carbonate.

후처리

  1. temperatureunder cooling with ice
  2. temperatureunder cooling with ice
  3. customA precipitate thus formed
  4. filtrationwas recovered by filtration
  5. washwashed with water
  6. dry with materialwith acetone, and dried

출처 및 근거

ORD 기록
ord-6cef8c273965478ab65e9f151f671b83
출처 데이터셋
uspto-grants-1990_08
특허 번호
US04948808

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