Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzalkonium Chloride → Hydrochloric Acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzalkonium Chloride | HCID 3014024 | — |
| 반응물 | Timolol Maleate | HCID 5281056 | — |
| 용매 | Sodium chloride; water | HCID 57417360 | — |
| 생성물 | Hydrochloric Acid | HCID 313 | — |
| 생성물 | Betaxolol Hydrochloride | HCID 107952 | — |
반응 단계
Timolol maleate powder was from Merck, Sharp and Dohme (West Point, Pa.) and was dissolved in 0.5% polysorbate 80 in normal saline with 0.01% benzalkonium chloride (40 mg/ml, and 20 mg/ml, respectively). Betaxolol hydrochloride (Betoptic; Alcon, Fort Worth, Tex.) at a concentration of 0.5% (5 mg/ml) and levobunalol hydrochloride (Betagan; Allergan, Irvine, Calif.) at a concentration of 0.5% (5 mg/ml), were obtained from the pharmacy.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04952581 |
| 출처 데이터셋 | uspto-grants-1990_08 |
| ORD ID | ord-7c2c3d85450b4229ba69dc8ec5a40455 |
| 출처 메모 | uspto-grants-1990_08 |