홈MCP워크벤치Skills
홈워크벤치알림마이페이지
llms.txt · MCP 가이드개인정보처리방침 · 이용약관 · 지원v1.8.0
  1. 홈
  2. /반응

Triethylamine → Phenoxyacetic Acid

HRID 1710306
노트
인쇄 미리보기

반응식

HRID 1710306 반응식
[N+]([O-])([O-])=O.[Nd+3:5].[N+]([O-])([O-])=O.[N+]([O-])([O-])=O.[O:14]([CH2:21][C:22]([OH:24])=[O:23])[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1.C(N(CC)CC)C>CO>[Nd:5].[O:14]([CH2:21][C:22]([OH:24])=[O:23])[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1
참가 물질반응 조건실험 절차후처리출처 및 근거반응 노트

참가 물질

6

반응물 3

HCID 8471TriethylamineHCID 19188Phenoxyacetic AcidHCID 10980413Neodymium(3+) hydrate trinitrate3회

생성물 2

HCID 19188Phenoxyacetic AcidHCID 23934Neodymium

시약·촉매·용매 1

HCID 887Methanol용매3회

반응 조건

온도
25 °C

실험 절차

The compound was synthesized by the same method as that for Synthesis Example 1-2 above, that is, after forming a triethylamine salt of phenoxyacetic acid in anhydrous methanol, a methanol solution of neodymium nitrate was added while stirring. Specifically, a reactor similar to that of 1-1 was used to stir a solution obtained by adding 100 ml of an anhydrous methanol to 45.65 g (0.3 mol) of phenoxyacetic acid, while dripping 30.4 g (0.3 mol) of triethylamine while maintaining at 25° C. by cooling in an ice water bath. After dripping, the solution was heated for 30 minutes at 40° C. to prepare a transparent synthesis solution of phenoxyacetic acid-triethylamine salts. Next, this synthesis solution was maintained at about 30° C., and a solution obtained by dissolving 43.8 g of neodymium nitrate into 100 ml of methanol was dripped in while stirring. Upon completion of the dripping of the neodymium nitrate solution, it began to cloud, and the clouding increased with time. 30 minutes after completion of dripping, the solution was heated to 40° C. for 30 minutes, to produce a slurry solution of a neodymium salt of phenoxyacetic acid. Crystals obtained by filtering this slurry solution were added to 200 ml of methanol, stirred and washed, then refiltered, and 200 ml of methanol were once again added to the crystals, stirred and washed, then filtered. The resulting crystals were dried under reduced pressure at 50° C., to obtain 38.8 g of a neodymium salt of phenoxyacetic acid (yield 65%).

후처리

  1. customSpecifically, a reactor similar to that of 1-1 was used
  2. stirringto stir a solution
  3. customobtained
  4. temperatureby cooling in an ice water bath
  5. temperaturethe solution was heated for 30 minutes at 40° C.
  6. temperatureNext, this synthesis solution was maintained at about 30° C.
  7. customa solution obtained
  8. stirringwhile stirring
  9. temperaturethe clouding increased with time
  10. custom30 minutes
  11. temperaturethe solution was heated to 40° C. for 30 minutes

출처 및 근거

ORD 기록
ord-f3aaec8856f24ac2b20a52a986e169b1
출처 데이터셋
uspto-grants-2010_09
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US07790290B2

반응 노트

불러오는 중…

이 페이지에서참가 물질반응 조건실험 절차후처리출처 및 근거반응 노트