Tert-butyl 4-(5-amino-2-methoxyphenyl)piperazine-1-carboxylate → HCID 67095168, 화합물

HRID 1710610노트

반응식

HRID 1710610 반응식
C(OC([N:8]1[CH2:13][CH2:12][N:11]([C:14]2[CH:19]=[C:18]([NH2:20])[CH:17]=[CH:16][C:15]=2[O:21][CH3:22])[CH2:10][CH2:9]1)=O)(C)(C)C.[F:23][CH:24]([F:38])[O:25][C:26]1[CH:27]=[CH:28][C:29]([O:36][CH3:37])=[C:30]([S:32]([Cl:35])(=[O:34])=[O:33])[CH:31]=1>>[ClH:35].[F:38][CH:24]([F:23])[O:25][C:26]1[CH:27]=[CH:28][C:29]([O:36][CH3:37])=[C:30]([S:32]([NH:20][C:18]2[CH:17]=[CH:16][C:15]([O:21][CH3:22])=[C:14]([N:11]3[CH2:10][CH2:9][NH:8][CH2:13][CH2:12]3)[CH:19]=2)(=[O:34])=[O:33])[CH:31]=1

참가 물질

3

반응물 2

HCID 10686178Tert-butyl 4-(5-amino-2-methoxyphenyl)piperazine-1-carboxylateHCID 66521642HCID 66521642, 화합물

생성물 1

HCID 67095168HCID 67095168, 화합물

실험 절차

The compound was prepared as described for Example 1 by reaction of 4-(5-amino-2-methoxy-phenyl)-piperazine-1-carboxylic acid tert-butyl ester with commercially available 5-difluoromethoxy-2-methoxybenzenesulfonylchloride followed by deprotection under acidic conditions.

후처리

  1. customThe compound was prepared

출처 및 근거

ORD 기록
ord-dc189945d9f14a92b24a50c026ecaa4d
출처 데이터셋
uspto-grants-2010_09
특허 번호
US07790727B2

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