2,2-Difluoro-2H-1,3-benzodioxole-4-sulfonyl chloride → HCID 86630402, 화합물
반응식
[F:1][C:2]1([F:15])[O:6][C:5]2[CH:7]=[CH:8][CH:9]=[C:10]([S:11]([Cl:14])(=[O:13])=[O:12])[C:4]=2[O:3]1.C([N:23]1[CH2:28][CH2:27][N:26]([C:29]2[CH:34]=[C:33]([NH2:35])[CH:32]=[CH:31][C:30]=2[O:36][CH2:37][CH2:38][F:39])[CH2:25][CH2:24]1)(OC(C)(C)C)=O>>[ClH:14].[F:39][CH2:38][CH2:37][O:36][C:30]1[C:29]([N:26]2[CH2:25][CH2:24][NH:23][CH2:28][CH2:27]2)=[CH:34][C:33]([NH:35][S:11]([C:10]2[C:4]3[O:3][C:2]([F:15])([F:1])[O:6][C:5]=3[CH:7]=[CH:8][CH:9]=2)(=[O:13])=[O:12])=[CH:32][CH:31]=1참가 물질
3
실험 절차
The compound was prepared as described for Example 9 using commercially available 2,2-Difluoro-benzo[1,3]dioxole-4-sulfonyl chloride and 1-(N-boc-piperazin-4-yl)-2-(2-fluoroethoxy)-5-aminobenzene from Example 11.
후처리
- customThe compound was prepared
출처 및 근거
- ORD 기록
- ord-ea2dfe805e564334bc7fe79f0153a1e8
- 출처 데이터셋
- uspto-grants-2010_09