4-(Difluoromethoxy)benzenesulfonyl chloride → HCID 67095209, 화합물
반응식
C(OC([N:8]1[CH2:13][CH2:12][N:11]([C:14]2[CH:19]=[C:18]([NH2:20])[CH:17]=[CH:16][C:15]=2[O:21][CH3:22])[CH2:10][CH2:9]1)=O)(C)(C)C.[F:23][CH:24]([F:36])[O:25][C:26]1[CH:31]=[CH:30][C:29]([S:32]([Cl:35])(=[O:34])=[O:33])=[CH:28][CH:27]=1>>[ClH:35].[F:36][CH:24]([F:23])[O:25][C:26]1[CH:27]=[CH:28][C:29]([S:32]([NH:20][C:18]2[CH:17]=[CH:16][C:15]([O:21][CH3:22])=[C:14]([N:11]3[CH2:10][CH2:9][NH:8][CH2:13][CH2:12]3)[CH:19]=2)(=[O:34])=[O:33])=[CH:30][CH:31]=1참가 물질
3
실험 절차
The compound was prepared as described for Example 1 by reaction of 4-(5-amino-2-methoxy-phenyl)-piperazine-1-carboxylic acid tert-butyl ester with commercially available 4-difluoromethoxy benzene sulfonylchloride followed by deprotection.
후처리
- customThe compound was prepared
출처 및 근거
- ORD 기록
- ord-e868af2767d041a296efd546e6c29875
- 출처 데이터셋
- uspto-grants-2010_09