2-Thiophenecarbonyl chloride → [3-Hydroxy-3-(3-methoxyphenyl)-piperidine-1-yl]-thiophen-2-yl-methanone
반응식
[S:1]1[CH:5]=[CH:4][CH:3]=[C:2]1[C:6](Cl)=[O:7].[CH3:9][O:10][C:11]1[CH:12]=[C:13]([C:17]2([OH:23])[CH2:22][CH2:21][CH2:20][NH:19][CH2:18]2)[CH:14]=[CH:15][CH:16]=1>>[OH:23][C:17]1([C:13]2[CH:14]=[CH:15][CH:16]=[C:11]([O:10][CH3:9])[CH:12]=2)[CH2:22][CH2:21][CH2:20][N:19]([C:6]([C:2]2[S:1][CH:5]=[CH:4][CH:3]=2)=[O:7])[CH2:18]1참가 물질
3
실험 절차
The compound of Example 14 was prepared according to the general preparation protocol A from thiophene-2-carbonyl chloride and 3-(3-methoxy-phenyl)-piperidine-3-ol.
출처 및 근거
- ORD 기록
- ord-622c623594e4484d991492aefea8144f
- 출처 데이터셋
- uspto-grants-2010_09
- 특허 번호
- US07790898B2
반응 노트
불러오는 중…