1,3-Dibromopropane → 1-(3-Bromopropoxy)-2,3-difluorobenzene

반응식

[F:1][C:2]1[C:7]([F:8])=[CH:6][CH:5]=[CH:4][C:3]=1[OH:9].[Br:10][CH2:11][CH2:12][CH2:13]Br>>[Br:10][CH2:11][CH2:12][CH2:13][O:9][C:3]1[CH:4]=[CH:5][CH:6]=[C:7]([F:8])[C:2]=1[F:1]

참가 물질

반응물 2

HCID 80011,3-Dibromopropane

HCID 808792,3-Difluorophenol

생성물 1

HCID 630386791-(3-Bromopropoxy)-2,3-difluorobenzene

실험 절차

Analogously to Example 91b, 2.00 g of 2,3-difluorophenol and 30.7 g of 1,3-dibromopropane are reacted. The title compound is obtained as a colourless oil. Rf=0.39 (1:10 EtOAc-heptane); Rt=4.82.

출처 및 근거

ORD 기록: ord-54e827ca3d934e418f23512db63c0781
출처 데이터셋: uspto-grants-2010_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07790715B2

반응 노트

불러오는 중…