4-Piperidinecarboxamide → 4'-(4-(2-Methoxy-phenylsulfanyl)-3-trifluoromethyl-phenyl)-3,4,5,6-tetrahydro-2H-(1,2')bipyridinyl-4-carboxylic acid amide

HRID 171283

반응식

HRID 171283 반응식
[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6](-[c:8]2[cH:9][c:10]([C:23]([F:24])([F:25])[F:26])[c:11]([S:14][c:15]3[c:16]([O:21][CH3:22])[cH:17][cH:18][cH:19][cH:20]3)[cH:12][cH:13]2)[cH:7]1.[NH:33]1[CH2:34][CH2:35][CH:36]([C:37](=[O:38])[NH2:39])[CH2:40][CH2:41]1.[OH:27][CH:28]1[CH2:29][CH2:30][NH:31][CH2:32]1>>[c:2]1([N:33]2[CH2:34][CH2:35][CH:36]([C:37](=[O:38])[NH2:39])[CH2:40][CH2:41]2)[n:3][cH:4][cH:5][c:6](-[c:8]2[cH:9][c:10]([C:23]([F:24])([F:25])[F:26])[c:11]([S:14][c:15]3[c:16]([O:21][CH3:22])[cH:17][cH:18][cH:19][cH:20]3)[cH:12][cH:13]2)[cH:7]1

참가 물질

4

반응물 3

HCID 37724-PiperidinecarboxamideHCID 982104-HydroxypyrrolidineHCID 219068092-Chloro-4-(4-(2-methoxy-phenylsulfanyl)-3-trifluoromethyl-phenyl)-pyridine

생성물 1

HCID 443919614'-(4-(2-Methoxy-phenylsulfanyl)-3-trifluoromethyl-phenyl)-3,4,5,6-tetrahydro-2H-(1,2')bipyridinyl-4-carboxylic acid amide

출처 및 근거

ORD 기록
ord-6e528885298f4c529d4bc0d5cd120d5a
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

연결된 노트

불러오는 중…