Formaldehyde → 2,3,4-Trihydroxy-5-(morpholin-4-ylmethyl)benzaldehyde

HRID 1714700

반응식

HRID 1714700 반응식
[NH:1]1[CH2:6][CH2:5][O:4][CH2:3][CH2:2]1.[CH2:7]=O.[OH:9][C:10]1[C:17]([OH:18])=[C:16]([OH:19])[CH:15]=[CH:14][C:11]=1[CH:12]=[O:13]>C(O)C>[OH:9][C:10]1[C:17]([OH:18])=[C:16]([OH:19])[C:15]([CH2:7][N:1]2[CH2:6][CH2:5][O:4][CH2:3][CH2:2]2)=[CH:14][C:11]=1[CH:12]=[O:13]

참가 물질

5

반응물 3

HCID 712FormaldehydeHCID 8083MorpholineHCID 750642,3,4-Trihydroxybenzaldehyde

생성물 1

HCID 592358932,3,4-Trihydroxy-5-(morpholin-4-ylmethyl)benzaldehyde

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

20.9 g (0.24 mol) of morpholine were added to 19.2 g (0.24 mol) of a 37% aqueous formaldehyde solution in 140 ml of ethanol. Then 25.0 g (0.16 mol) of 2,3,4-trihydroxybenzaldehyde were added thereto. The reaction mixture was refluxed for one hour, developing a dark brown color. After cooling, a beige-brown solid precipitated out, which was filtered out and dried.

후처리

  1. temperatureThe reaction mixture was refluxed for one hour
  2. temperatureAfter cooling
  3. customa beige-brown solid precipitated out
  4. filtrationwhich was filtered out
  5. customdried

출처 및 근거

ORD 기록
ord-89941800135d4dd383ca1570a6628d70
출처 데이터셋
uspto-grants-2010_09
특허 번호
US07799096B2

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