Dimethylformamide → 1-(3-(2-Fluoropropan-2-yl)isoxazol-5-yl)-3-(3-(6-hydroxy-7-methoxyquinazolin-4-yloxy)phenyl)urea

반응식

[F:22][C:23]([CH3:24])([CH3:25])[c:26]1[n:27][o:28][c:29]([NH:31][C:32]([O:33][c:35]2[cH:36][cH:37][c:38]([Cl:39])[cH:40][cH:41]2)=[O:34])[cH:30]1.[NH2:1][c:2]1[cH:3][c:4]([O:5][c:6]2[n:7][cH:8][n:9][c:10]3[cH:11][c:12]([O:17][CH3:18])[c:13]([OH:16])[cH:14][c:15]23)[cH:19][cH:20][cH:21]1.[O:42]=[CH:43][N:44]([CH3:45])[CH3:46]>>[NH:1]([c:2]1[cH:3][c:4]([O:5][c:6]2[n:7][cH:8][n:9][c:10]3[cH:11][c:12]([O:17][CH3:18])[c:13]([OH:16])[cH:14][c:15]23)[cH:19][cH:20][cH:21]1)[C:32]([NH:31][c:29]1[o:28][n:27][c:26]([C:23]([F:22])([CH3:24])[CH3:25])[cH:30]1)=[O:33]