6-Bromoindole → HCID 72573301, 화합물

반응식

Br[C:2]1[CH:10]=[C:9]2[C:5]([CH:6]=[CH:7][NH:8]2)=[CH:4][CH:3]=1.N1[C:19]2[C:14](=[C:15]([C:20](C3C=CC=CC=3)=[CH:21][C:22]#[N:23])[CH:16]=[CH:17][CH:18]=2)C=C1>>[NH:8]1[C:9]2[C:5](=[CH:4][CH:3]=[C:2]([C:20]([C:15]3[CH:16]=[CH:17][CH:18]=[CH:19][CH:14]=3)=[CH:21][C:22]#[N:23])[CH:10]=2)[CH:6]=[CH:7]1

참가 물질

반응물 2

HCID 6764936-Bromoindole

HCID 72573307HCID 72573307, 화합물

생성물 1

HCID 72573301HCID 72573301, 화합물수율 61%

실험 절차

3-(1H-Indol-6-yl)-3-phenyl-acrylonitrile XII (1.46 g, 61% yield) was prepared from 6-bromo-indole using the procedure described for 3-(1H-indol-4-yl)-3-phenyl-acrylonitrile I.

출처 및 근거

ORD 기록: ord-68bf410e6f724c2599047b50a25575c3
출처 데이터셋: uspto-grants-2010_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07803830B2

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