3-Pyridineacrylic acid ethyl ester → 3-(3-Methoxy-1H-indazol-6-yl)-3-pyridin-3yl-acrylic acid ethyl ester

HRID 1716768노트

반응식

HRID 1716768 반응식
Br[C:2]1[CH:10]=[C:9]2[C:5]([C:6]([O:11][CH3:12])=[N:7][NH:8]2)=[CH:4][CH:3]=1.[CH2:13]([O:15][C:16](=[O:25])[CH:17]=[CH:18][C:19]1[CH:20]=[N:21][CH:22]=[CH:23][CH:24]=1)[CH3:14]>>[CH2:13]([O:15][C:16](=[O:25])[CH:17]=[C:18]([C:2]1[CH:10]=[C:9]2[C:5]([C:6]([O:11][CH3:12])=[N:7][NH:8]2)=[CH:4][CH:3]=1)[C:19]1[CH:20]=[N:21][CH:22]=[CH:23][CH:24]=1)[CH3:14]

참가 물질

3

반응물 2

HCID 5833373-Pyridineacrylic acid ethyl esterHCID 598318906-Bromo-3-methoxy-1H-indazole

생성물 1

HCID 673561423-(3-Methoxy-1H-indazol-6-yl)-3-pyridin-3yl-acrylic acid ethyl ester

실험 절차

3-(3-Methoxy-1H-indazol-6-yl)-3-pyridin-3yl-acrylic acid ethyl ester was prepared from 6-bromo-3-methoxy-1H-indazole and 3-pyridin-3-yl-acrylic acid ethyl ester using the procedure described for preparation of 3-(3-Cyano-1H-Indol-4-yl)-3-phenyl-acrylic acid ethyl esterLVIII (Example 14).

출처 및 근거

ORD 기록
ord-a95d9bf198c548cfb798d706abb581bf
출처 데이터셋
uspto-grants-2010_09
특허 번호
US07803830B2

반응 노트

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