Ethyl 3-(3-Aminophenyl)propionate → 3-(3-{[6-Bromo-pyridine-2-carbonyl)-amino]-phenyl}-propionic acid ethyl ester

HRID 1717152

반응식

HRID 1717152 반응식
[Br:1][C:2]1[N:7]=[C:6]([C:8]([OH:10])=O)[CH:5]=[CH:4][CH:3]=1.[CH2:11]([O:13][C:14](=[O:24])[CH2:15][CH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[C:19]([NH2:23])[CH:18]=1)[CH3:12]>>[CH2:11]([O:13][C:14](=[O:24])[CH2:15][CH2:16][C:17]1[CH:22]=[CH:21][CH:20]=[C:19]([NH:23][C:8]([C:6]2[CH:5]=[CH:4][CH:3]=[C:2]([Br:1])[N:7]=2)=[O:10])[CH:18]=1)[CH3:12]

참가 물질

3

반응물 2

HCID 82314Ethyl 3-(3-Aminophenyl)propionateHCID 5939196-Bromopyridine-2-carboxylic acid

생성물 1

HCID 596548223-(3-{[6-Bromo-pyridine-2-carbonyl)-amino]-phenyl}-propionic acid ethyl ester

실험 절차

6-Bromo-pyridine-2-carboxylic acid (261 mg, 1.29 mmol) was coupled to aniline (124) (250 mg, 1.29 mmol) using Method C to give the title compound.

출처 및 근거

ORD 기록
ord-28b01834cd144ec993105e2339466230
출처 데이터셋
uspto-grants-2010_09
특허 번호
US07803841B2

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