Methanesulfenylchloride → 1-[(Chloromethoxy)methyl]naphthalene

HRID 1719234노트

반응식

HRID 1719234 반응식
S(Cl)(Cl)(=O)=O.C1C2C(=CC=CC=2)C=CC=1.[C:16]1([CH2:26][O:27][CH2:28]SC)[C:25]2[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=2)[CH:19]=[CH:18][CH:17]=1.CS[Cl:33]>ClCCl>[Cl:33][CH2:28][O:27][CH2:26][C:16]1[C:25]2[C:20](=[CH:21][CH:22]=[CH:23][CH:24]=2)[CH:19]=[CH:18][CH:17]=1

참가 물질

5

반응물 3

HCID 138595MethanesulfenylchlorideHCID 15650475Methylthiomethyl 1-naphthylmethyl etherHCID 22556242HCID 22556242, 화합물

생성물 1

HCID 134082881-[(Chloromethoxy)methyl]naphthalene

시약·촉매·용매 1

HCID 6344Dichloromethane용매2회

실험 절차

1-Chloromethyloxymethyl)naphthalene Sulfuryl chloride (12 mmol) in dry dichloromethane (20 mmol) was added dropwise with stirring to a solution of methylthiomethyl 1-naphthylmethyl ether (12 mmol) in dry dichloromethane (40 ml) at room temperature. After stirring for 30 min the solvent and methanesulfenyl chloride formed in the reaction were distilled off at reduced pressure. The residual material was used for alkylation without further purification. 1H NMR (CDCl3): δ5.13 (CH2), 5.47 (CH2Cl), 7.2-8.3 (Naph).

후처리

  1. customformed in the reaction
  2. distillationwere distilled off at reduced pressure
  3. customThe residual material was used for alkylation without further purification

출처 및 근거

ORD 기록
ord-a69b9863163d4784871dc425371f3af4
출처 데이터셋
uspto-grants-1985_09
특허 번호
US04539324

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