2,3-Dimethyl-6-nitroquinoxaline → 6-Quinoxalinamine, 2,3-dimethyl-

HRID 1719495노트

반응식

HRID 1719495 반응식
[CH3:1][C:2]1[C:11]([CH3:12])=[N:10][C:9]2[C:4](=[CH:5][CH:6]=[C:7]([N+:13]([O-])=O)[CH:8]=2)[N:3]=1.[H][H]>[Pd]>[NH2:13][C:7]1[CH:8]=[C:9]2[C:4](=[CH:5][CH:6]=1)[N:3]=[C:2]([CH3:1])[C:11]([CH3:12])=[N:10]2

참가 물질

4

반응물 2

HCID 6089992,3-Dimethyl-6-nitroquinoxalineHCID 178418361HCID 178418361, 화합물

생성물 1

HCID 1460536-Quinoxalinamine, 2,3-dimethyl-

시약·촉매·용매 1

HCID 23938Palladium촉매

실험 절차

A near solution of 2,3-dimethyl-6-nitroquinoxaline (62.9 g, 0.31 mole) in 1 L of absolute alcohol (Mallinkrodt) was hydrogenated in Parr apparatus using 5% Palladium on carbon 50% wet catalyst (Englehard). Hydrogen uptake (100% of theory) in 2 hours was noted. After the reduction stopped the catalyst was removed by filtration and the filtrate remaining concentrated to dryness in vacuo. The residue remaining was used without further purification as an intermediate in part C. Yield 52 g (96%).

후처리

  1. customwas removed by filtration
  2. concentrationthe filtrate remaining concentrated to dryness in vacuo
  3. customThe residue remaining was used without further purification as an intermediate in part C

출처 및 근거

ORD 기록
ord-3760b66f7ddb4819b045f7fdcfb7243d
출처 데이터셋
uspto-grants-1985_09
특허 번호
US04540693

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