Potassium Carbonate → HCID 135759101, 화합물
반응식
Cl.N[C:3]1[C:4]2[C:5](=[N:15][N:16]([CH3:18])[CH:17]=2)[NH:6][C:7]2[CH:13]=[CH:12][C:11]([Cl:14])=[CH:10][C:8]=2[N:9]=1.C(=O)([O-])[O-:20].[K+].[K+]>C(O)C.O>[Cl:14][C:11]1[CH:12]=[CH:13][C:7]2[NH:6][C:5]3=[N:15][N:16]([CH3:18])[CH:17]=[C:4]3[C:3](=[O:20])[NH:9][C:8]=2[CH:10]=1참가 물질
5
실험 절차
4-Amino-7-chloro-2,10-dihydro-2-methylpyrazolo[3,4-b][1,5]benzodiazepine hydrochloride (11.3 g) and potassium carbonate (16.8 g) were heated under reflux in a mixture of ethanol (200 ml) and water (20 ml) for 48 hours. Water (300 ml) was added and the solution cooled. The precipitate was crystallised from acetic acid to give the title compound m.p.>260° C.
후처리
- temperaturethe solution cooled
- customThe precipitate was crystallised from acetic acid
출처 및 근거
- ORD 기록
- ord-a1c9faef27364deb9a04b610f5e90160
- 출처 데이터셋
- uspto-grants-1985_09
- 특허 번호
- US04542131
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