Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzeneacetonitrile, alpha-hydroxy-3-phenoxy-, (alphaR)- → (R)alpha-cyano-3-phenoxy-benzyl(1R,cis)2,2-dimethyl-3-[(Z)3-oxo-3-(2,2-difluoroethoxy)-1-propenyl]-cyclopropane-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzeneacetonitrile, alpha-hydroxy-3-phenoxy-, (alphaR)- | HCID 156232 | — |
| 반응물 | (1R,cis)2,2-dimethyl-3-[(Z)3-oxo-3-(2,2-difluoroethoxy)-1-propenyl]cyclopropane-carboxylic acid | HCID 86740318 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | (R)alpha-cyano-3-phenoxy-benzyl(1R,cis)2,2-dimethyl-3-[(Z)3-oxo-3-(2,2-difluoroethoxy)-1-propenyl]-cyclopropane-carboxylate | HCID 86740317 | — |
반응 단계
Using the procedure of Step F of Example 9, (1R,cis) 2,2-dimethyl-3-[(Z) 3-oxo-3-(2,2-difluoroethoxy)-1 propenyl]-cyclopropane-carboxylic acid and (R)α-cyano-3-phenoxy-benzyl alcohol were reacted to obtain (R)α-cyano-3-phenoxy-benzyl (1R,cis) 2,2-dimethyl-3-[(Z) 3-oxo-3-(2,2-difluoroethoxy)-1-propenyl]-cyclopropane-carboxylate with a specific rotation of [α]D20 =+117.5°±3° (c=0.6% in chloroform).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04542142 |
| 출처 데이터셋 | uspto-grants-1985_09 |
| ORD ID | ord-2bcbeb4a713b4263bc3201dcd949eb98 |
| 출처 메모 | uspto-grants-1985_09 |