1,3-Dimethyl-2-imidazolidinone → 3-Phenoxybenzyl alcohol

반응식

CN1CCN(C)[C:3]1=[O:8].Cl[C:10]1[CH:11]=[C:12](C(C)(C)CCl)[CH:13]=[CH:14][C:15]=1[O:16][CH2:17][CH3:18]>>[O:16]([C:15]1[CH:10]=[C:11]([CH:12]=[CH:13][CH:14]=1)[CH2:3][OH:8])[C:17]1[CH:18]=[CH:14][CH:15]=[CH:10][CH:11]=1

참가 물질

반응물 2

HCID 66611,3-Dimethyl-2-imidazolidinone2회

HCID 52687462-Chloro-4-(2-chloro-1,1-dimethylethyl)-1-ethoxybenzene

생성물 1

HCID 262953-Phenoxybenzyl alcohol수율 500%

실험 절차

3 l (3,156 g) of 1,3-dimethyl-2-imidazolidinone (hereinafter referred to as DMI), 618.0 g (2.50 mol) of purified 2-(3-chloro-4-ethoxyphenyl)-2-methylpropyl chloride obtained in the same manner as in Example 1, 1,251.0 g (6.25 mol) of m-phenoxybenzyl alcohol (a product of Ethyl Corp.) and 280.0 g (5.00 mol) of potassium hydroxide in the form of flakes were charged in a 5 l four-neck flask and stirred at 120° C. under nitrogen stream for 15 h to complete the reaction.

출처 및 근거

ORD 기록: ord-e98a9814729042de9c6966ebdf21f885
출처 데이터셋: uspto-grants-1985_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04542243

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