1-(2-Tetrahydropyranyl)-4-[2-(2-tetrahydropyranyl)oxyethyl]-2-azetidinone → HCID 131712809, 화합물

반응식

[CH2:1]([C@H:8]1[C@H:11]([CH2:12][CH2:13][OH:14])[NH:10][C:9]1=[O:15])C1C=CC=CC=1.O1CCCCC1N1C(CCOC2CCCCO2)CC1=O>>[CH3:1][C@H:8]1[C@@H:11]([CH2:12][CH2:13][OH:14])[NH:10][C:9]1=[O:15]

참가 물질

반응물 2

HCID 143289841-(2-Tetrahydropyranyl)-4-[2-(2-tetrahydropyranyl)oxyethyl]-2-azetidinone

HCID 67926856HCID 67926856, 화합물

생성물 1

HCID 131712809HCID 131712809, 화합물

실험 절차

Following the procedure described for the preparation of trans-3-benzyl-4-(2-hydroxyethyl)-2-azetidinone from 8-oxo-2,2-dimethyl-7α-benzyl-3-oxa-1-azabicyclo[4.2.0]octane and using 8-oxo-2,2-dimethyl-7β-methyl-3-oxa-1-azabicyclo[4.2.0]octane one obtains cis-3-methyl-4-(2'-hydroxyethyl)-2-azetidinone.

출처 및 근거

ORD 기록: ord-1b5b269ed9d24fefb8ea3a59b7600d09
출처 데이터셋: uspto-grants-1985_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04543257

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