Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Pentylbenzene → 6-Oxo-6-(4-pentylphenyl)hexanoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Pentylbenzene | HCID 10864 | — |
| 반응물 | monoMethyl adipate | HCID 12328 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | Thionyl Chloride | HCID 24386 | — |
| 반응물 | Aluminum(III) Chloride | HCID 6451240 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 6-Oxo-6-(4-pentylphenyl)hexanoic acid | HCID 15295559 | — |
반응 단계
Adipic acid monomethyl ester (35 g; 0.44 mole) is converted to the acid chloride with thionyl chloride (50 g) in a manner analogous to that described in Example 1. This product is reacted with pentylbenzene (400 ml) and aluminum chloride (80 g) and the reaction product isolated as a colorless oil (25 g; b.p. 165°-174° C. @0.15 mm) and identified as methyl 5-(4-n-pentylbenzoyl) pentanoate. This ester (5 g; 0.017 mole) is hydrolysed with sodium hydroxide in aqueous ethanol and the product isolated as in Example 1. Recrystallization from aqueous ethanol gives 5-(4-n-pentylbenzoyl)pentanoic acid (4.0 g) as colorless crystals, m.p. 84°-86° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05504244 |
| 출처 데이터셋 | uspto-grants-1996_04 |
| ORD ID | ord-51f7c4be389a45bdb198c848b9091a7e |
| 출처 메모 | uspto-grants-1996_04 |