Atreleuton → HCID 86749397, 화합물

HRID 1720443

반응식

[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([CH2:8][C:9]2[S:13][C:12]([C:14]#[C:15][C@H:16]([N:18]([OH:22])[C:19]([NH2:21])=[O:20])[CH3:17])=[CH:11][CH:10]=2)=[CH:4][CH:3]=1.FC1C=CC(CC2SC(C#C[C@H](N(O)C(N)=O)C)=CC=2)=CC=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:8][C:9]2[S:13][C:12](/[CH:14]=[CH:15]\[C@H:16]([N:18]([OH:22])[C:19]([NH2:21])=[O:20])[CH3:17])=[CH:11][CH:10]=2)=[CH:6][CH:7]=1

참가 물질

반응물 2

HCID 3086671Atreleuton

HCID 53890623HCID 53890623, 화합물

생성물 1

HCID 86749397HCID 86749397, 화합물

실험 절차

The desired compound is prepared according to the method of Example 1, step 5, except substituting (R)-N-{3-[5-(4-chlorophenylmethyl)thien-2-yl]-1-methyl-2-propynyl}-N-hydroxyurea, prepared as in step 4, for (R)-N-{3-[5-(4-fluorophenylmethyl)thien-2-yl]-1-methyl-2-propynyl}-N-hydroxyurea.

출처 및 근거

ORD 기록: ord-4d46b8df6f64485985d17b128c79e0a1
출처 데이터셋: uspto-grants-1996_04
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05506261

연결된 노트

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