Methanethiol → Ethyl 2-ethylthiomethyl-4-methylpentanoate
반응식
[CH2:1]([C:5](=[CH2:11])[C:6]([O:8][CH2:9][CH3:10])=[O:7])[CH:2]([CH3:4])[CH3:3].C[C:13]([CH3:16])([O-])C.[K+].C[SH:19]>C(OCC)(=O)C>[CH2:13]([S:19][CH2:11][CH:5]([CH2:1][CH:2]([CH3:4])[CH3:3])[C:6]([O:8][CH2:9][CH3:10])=[O:7])[CH3:16]참가 물질
5
실험 절차
650 mg of ethyl 2-isobutyl-2-propenoate was dissolved in 3 ml of methylmercaptan, and 50 mg of potassium tert-butoxide was added thereto. The mixture was stirred at room temperature for two hours. The reaction solution was diluted with 60 ml of ethyl acetate, washed with water and then with a saturated sodium chloride aqueous solution and dried over anhydrous sodium sulfate. The solvent was distilled off under reduced pressure to obtain 660 mg of ethyl 2-ethylthiomethyl-4-methylpentanoate as colorless oily substance.
후처리
- washwashed with water
- dry with materialwith a saturated sodium chloride aqueous solution and dried over anhydrous sodium sulfate
- distillationThe solvent was distilled off under reduced pressure
출처 및 근거
- ORD 기록
- ord-b260e60e8d42432c9ae1c67fa8bcd51f
- 출처 데이터셋
- uspto-grants-1996_04
- 특허 번호
- US05506356
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