Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → N-(1-Methyl-5-indolyl)-N'-(4-isoquinolyl) urea
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| 반응물 | 4-Aminoisoquinoline | HCID 90237 | — |
| 반응물 | 1-methyl-1H-indol-5-amine | HCID 2769564 | — |
| 용매 | Diethyl ether ethanol | HCID 21585056 | — |
| 생성물 | N-(1-Methyl-5-indolyl)-N'-(4-isoquinolyl) urea | HCID 22416532 | — |
반응 단계
The title compound was prepared from 4-aminoisoquinoline, 1,1'-carbonyl diimidazole and 5-amino-1-methyl-indole using a procedure similar to that described for Example 1, and then converted to the hydrochloride salt using hydrogen chloride in ether/ethanol, in 26% overall yield, m.p. 195°-197° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05508288 |
| 출처 데이터셋 | uspto-grants-1996_04 |
| ORD ID | ord-215ab40df9634630af5f9a7d20aca993 |
| 출처 메모 | uspto-grants-1996_04 |