N-bromobutanimide → 2-Ethoxycarbonylimino-3-(3-trifluoromethylpheny)-5-bromothiazoline

참여 물질

반응 단계

A solution of 2-ethoxycarbonylimino-3-(3-trifluoromethylphenyl) thiazolidine (1.6 g) and N-bromosuccinimide (2 g) in chloroform (50 ml) was refluxed for 10 hours. After cooling, the reaction mixture was washed with an aqueous sodium sulfite solution and dried over anhydrous magnesium sulfate. The solvent was removed under reduced pressure, and the residue was subjected to column chromatography to give 0.9 g of 2-ethoxycarbonylimino-3-(3-trifluoromethylphenyl)-5-bromothiazoline (Compound No. 30).

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