1-Chloro-2,4,6-trifluorobenzene → 1,3,5-Trifluorobenzene
반응식
Cl[C:2]1[C:7]([F:8])=[CH:6][C:5]([F:9])=[CH:4][C:3]=1[F:10]>[Cu].O>[F:8][C:7]1[CH:2]=[C:3]([F:10])[CH:4]=[C:5]([F:9])[CH:6]=1참가 물질
4
반응 조건
- 온도
- 300 °C
실험 절차
An autoclave was charged with 66.8 g of 2-chloro-1,3,5-trifluorobenzene, 5 g of water and 65 g of copper powder, and the content was heated at 300° C. with high speed stirring for 28 hours. After the reaction, the content was distilled off, and the fraction distilled at 74° to 77° C. was collected and dried over sodium sulfate to obtain 1,3,5-trifluorobenzene in an amount of 38.5 g (yield 73%).
후처리
- customAfter the reaction
- distillationthe content was distilled off
- distillationthe fraction distilled at 74° to 77° C.
- customwas collected
- dry with materialdried over sodium sulfate
출처 및 근거
- ORD 기록
- ord-ac4b01011aac41659487e486ddda1a3f
- 출처 데이터셋
- uspto-grants-1996_04
- 특허 번호
- US05510533
반응 노트
불러오는 중…