Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetyl chloride → 1-Acetyl-5-amino-3-benzylthio-1,2,4-triazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetyl chloride | HCID 6367 | — |
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | 5-(benzylsulfanyl)-4H-1,2,4-triazol-3-amine | HCID 737272 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 1-Acetyl-5-amino-3-benzylthio-1,2,4-triazole | HCID 14255122 | — |
반응 단계
To 30 g (0.145 mol) 5-amino-3-benzylthio-1H-1,2,4-triazole and 25 ml triethylamine in 300 ml methylene chloride, 12.57 g (0.16 mol) acetyl chloride in 30 ml methylene chloride was added dropwise. It was then stirred at room temperature for 30 minutes, treated with 160 ml 1N caustic soda and the product extracted with methylene chloride. After drying it was recrystallised from ethyl acetate.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04859231 |
| 출처 데이터셋 | uspto-grants-1989_08 |
| ORD ID | ord-750e84dd79d44b36b62808683548c0fc |
| 출처 메모 | uspto-grants-1989_08 |