Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → ethyl N-(4-formyl-2-nitrophenyl)glycine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Sodium Bicarbonate | HCID 516892 | — |
| 반응물 | 4-Fluoro-3-nitrobenzaldehyde | HCID 598129 | — |
| 반응물 | 2-(Ethylamino)acetic acid hydrochloride | HCID 19011402 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | ethyl N-(4-formyl-2-nitrophenyl)glycine | HCID 86743322 | 79% |
반응 단계
(a-1) To a stirred solution of 1.4 parts of ethyl glycine hydrochloride in 10 parts of water was added a solution of 1.7 parts of 4-fluoro-3-nitrobenzaldehyde in 8 parts of ethanol. Then there were added 1.76 parts of sodium hydrogen carbonate and stirring at room temperature was continued for 48 hours. The precipitated product was filtered off, washed successively with water, ethanol and 2,2'-oxybispropane, and dried, yielding 2 parts (79%) of ethyl N-(4-formyl-2-nitrophenyl)-glycine; mp. 90° C. (int. 29).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04859684 |
| 출처 데이터셋 | uspto-grants-1989_08 |
| ORD ID | ord-8b14977da1324c5595970fe82a0ca1ef |
| 출처 메모 | uspto-grants-1989_08 |