Bromine → 4-Bromo-2,6-difluoropyridine

HRID 1724058노트

반응식

HRID 1724058 반응식
[F:1][C:2]1[CH:7]=[C:6](B(O)O)[CH:5]=[C:4]([F:11])[N:3]=1.FC1C=C(NN)C=C(F)N=1.[Br:22]Br>>[Br:22][C:6]1[CH:7]=[C:2]([F:1])[N:3]=[C:4]([F:11])[CH:5]=1

참가 물질

4

반응물 3

HCID 24408BromineHCID 27627472,6-Difluoropyridine-4-boronic acidHCID 121758102,6-Difluoro-4-hydrazinylpyridine

생성물 1

HCID 220155594-Bromo-2,6-difluoropyridine

실험 절차

The second step in the synthetic procedure used in synthesizing the 2,6-difluoropyridin-4-ylboronic acid involves bromination of 2,6-difluoro-4-hydrazinopyridine by elemental bromine to produce 4-bromo-2,6-difluoropyridine. This reaction can be depicted as follows:

출처 및 근거

ORD 기록
ord-178d2f65bba74d9ea9cd76ace67e8497
출처 데이터셋
uspto-grants-2009_02
특허 번호
US07485725B1

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