2,5-Dimethylpiperazine, trans- → HCID 136360191, 화합물

HRID 1725431노트

반응식

HRID 1725431 반응식
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[NH:11][C:10]3[CH:12]=[CH:13][CH:14]=[CH:15][C:9]=3[C:8](=O)[NH:7][C:6]=2[CH:17]=1.[CH3:18][C@H:19]1[CH2:24][NH:23][C@H:22]([CH3:25])[CH2:21][NH:20]1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[NH:11][C:10]3[CH:12]=[CH:13][CH:14]=[CH:15][C:9]=3[C:8]([N:20]3[CH2:21][C@@H:22]([CH3:25])[NH:23][CH2:24][C@@H:19]3[CH3:18])=[N:7][C:6]=2[CH:17]=1

참가 물질

3

반응물 2

HCID 2206722,5-Dimethylpiperazine, trans-HCID 36531168-chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one

생성물 1

HCID 136360191HCID 136360191, 화합물수율 5.6%

실험 절차

8-Chloro-5,10-dihydro-dibenzo[b,e][1,4]diazepine-11-one (25 mg, 0.1 mmol) and trans-2,5-dimethylpiperazine (114 mg, 1.0 mmol) were reacted according to GP4 to give 1.9 mg of the title compound (160FE33A). MS (ESI) 341 (MH+). Purity for MH+ (UV/MS) 100/82.

출처 및 근거

ORD 기록
ord-814f8a25ade0435ca527c4066bb1d1e1
출처 데이터셋
uspto-grants-2009_02
특허 번호
US07491715B2

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