Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
tert-butyl 4-(1H-imidazol-2-yl)-3,6-dihydropyridine-1(2H)-carboxylate → tert-butyl 4-(1H-imidazol-2-yl)piperidine-1-carboxylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | tert-butyl 4-(1H-imidazol-2-yl)-3,6-dihydropyridine-1(2H)-carboxylate | HCID 69053296 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | tert-butyl 4-(1H-imidazol-2-yl)piperidine-1-carboxylate | HCID 17840015 | 99.2% |
반응 단계
A mixture of tert-butyl 4-(1H-imidazol-2-yl)-3,6-dihydropyridine-1(2H)-carboxylate (7.5 g) and palladium on carbon (10%, 1 g) in ethanol (150 mL) was hydrogenated at 30 psi overnight. The catalyst was removed by filtration through celite and the filtrate was evaporated to give tert-butyl 4-(1H-imidazol-2-yl)piperidine-1-carboxylate (7.5 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07491737B2 |
| 출처 데이터셋 | uspto-grants-2009_02 |
| ORD ID | ord-b5455f3b58794e18851cd3d8ae8c03ae |
| 출처 메모 | uspto-grants-2009_02 |