Cyanogen Bromide → 1-(2-Methoxyethyl)-4,5-dihydro-1H-imidazol-2-amine hydrobromide
반응식
[CH3:1][O:2][CH2:3][CH2:4][NH:5][CH2:6][CH2:7][NH2:8].[N:9]#[C:10][Br:11]>>[BrH:11].[CH3:1][O:2][CH2:3][CH2:4][N:5]1[CH2:6][CH2:7][N:8]=[C:10]1[NH2:9]참가 물질
3
실험 절차
Reaction of N-(2-methoxyethyl)ethylenediamine (16.0 g, 0.135 mol) (R. C. F. Jones and J. R. Nichols, Tetrahedron Lett., 1990, 31, 1767-1770) with cyanogen bromide (14.34 g, 0.135 mol) as described in the preparation of intermediate 6 gave 26.86 g (88% yield) of the title product as large white prisms (ethanol); mp 143-145° C.
출처 및 근거
- ORD 기록
- ord-58bcca3207fa48cb821afaf560a4aa07
- 출처 데이터셋
- uspto-grants-2009_02
- 특허 번호
- US07494984B2
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