Sodium Bicarbonate → N-Phenyl-N'-{4-[4-(1H-pyrrolo[2,3-b]pyridin-4-yl)-1-(2,2,2-trifluoroethyl)-1H-pyrazol-3-yl]phenyl}urea

반응식

Br[C:2]1[C:3]([C:12]2[CH:17]=[CH:16][C:15]([NH:18][C:19]([NH:21][C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)=[O:20])=[CH:14][CH:13]=2)=[N:4][N:5]([CH2:7][C:8]([F:11])([F:10])[F:9])[CH:6]=1.CC1(C)C(C)(C)OB([C:36]2[CH:41]=[CH:40][N:39]=[C:38]3[NH:42][CH:43]=[CH:44][C:37]=23)O1.C(=O)(O)[O-].[Na+]>C1C=CC([P]([Pd]([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)([P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)[P](C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)(C2C=CC=CC=2)C2C=CC=CC=2)=CC=1.CN(C)C=O>[C:22]1([NH:21][C:19]([NH:18][C:15]2[CH:16]=[CH:17][C:12]([C:3]3[C:2]([C:36]4[CH:41]=[CH:40][N:39]=[C:38]5[NH:42][CH:43]=[CH:44][C:37]=45)=[CH:6][N:5]([CH2:7][C:8]([F:11])([F:10])[F:9])[N:4]=3)=[CH:13][CH:14]=2)=[O:20])[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1