Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-(4-Methoxyphenyl)but-3-en-2-one → 2-Amino-6-methyl-4-(4-methoxyphenyl)-1,4-dihydropyridine-3-carboxylic acid ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-(4-Methoxyphenyl)but-3-en-2-one | HCID 95414 | — |
| 반응물 | Carbamimidoyl-acetic acid ethyl ester | HCID 4599837 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 2-Amino-6-methyl-4-(4-methoxyphenyl)-1,4-dihydropyridine-3-carboxylic acid ethyl ester | HCID 12391099 | 52% |
반응 단계
Heating a solution of 17.5 g of 4-methoxybenzylideneacetone and 13.0 g of amidinoacetic acid ethyl ester in 150 ml of ethanol for 2 hours yields 2-amino-6-methyl-4-(4-methoxyphenyl)-1,4-dihydropyridine-3-carboxylic acid ethyl ester of melting point 160°-161°C (ethanol). Yield: 52 percent theory.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US03989708 |
| 출처 데이터셋 | uspto-grants-1976_11 |
| ORD ID | ord-12e8f636cc38462cb0102bead05fb21b |
| 출처 메모 | uspto-grants-1976_11 |