Water → 1-(Cyanoamino)nonan-4-yl acetate

HRID 1729909노트

반응식

HRID 1729909 반응식
[C:1]([O:4][CH:5]([CH2:13][CH2:14][CH2:15][CH2:16][CH3:17])[CH2:6][CH2:7][CH2:8][NH:9][C:10]([NH2:12])=O)(=[O:3])[CH3:2].C1(C)C=CC(S(Cl)(=O)=O)=CC=1.O>N1C=CC=CC=1>[C:1]([O:4][CH:5]([CH2:13][CH2:14][CH2:15][CH2:16][CH3:17])[CH2:6][CH2:7][CH2:8][NH:9][C:10]#[N:12])(=[O:3])[CH3:2]

참가 물질

5

반응물 3

HCID 962WaterHCID 73974-Toluenesulfonyl chlorideHCID 215014481-(Carbamoylamino)nonan-4-yl acetate

생성물 1

HCID 215014751-(Cyanoamino)nonan-4-yl acetate

시약·촉매·용매 1

HCID 1049Pyridine용매

실험 절차

To a stirred solution of 4-acetoxynonylurea (2.4 g., 0.01 mole) in pyridine (10 ml.) is added p-toluene-sulfonyl chloride (2.0 g., excess) in one portion. The reaction is stirred at room temperature for six hours then poured into water (150 ml.). The aqueous mixture is extracted with ether (3 × 75 ml.), the ether is washed with 5% hydrochloric acid, brine, and dried over sodium sulfate. The solvent is removed in vacuo to give 4-acetoxynonylcyanamide as a residual oil.

후처리

  1. extractionThe aqueous mixture is extracted with ether (3 × 75 ml.)
  2. washthe ether is washed with 5% hydrochloric acid, brine
  3. dry with materialdried over sodium sulfate
  4. customThe solvent is removed in vacuo

출처 및 근거

ORD 기록
ord-88c125c3ae62404296102bc7e732935a
출처 데이터셋
uspto-grants-1976_11
특허 번호
US03989749

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