Diethyl(2-isothiocyanatoethyl)amine → 8-(2-Diethylaminoethyl)thiocarbamoylamino-3-methyl-5,6,7,8-tetrahydroquinoline

반응식

[NH2:1][CH:2]1[C:11]2[N:10]=[CH:9][C:8]([CH3:12])=[CH:7][C:6]=2[CH2:5][CH2:4][CH2:3]1.[CH2:13]([N:15]([CH2:18][CH2:19][N:20]=[C:21]=[S:22])[CH2:16][CH3:17])[CH3:14]>>[CH2:13]([N:15]([CH2:16][CH3:17])[CH2:18][CH2:19][NH:20][C:21]([NH:1][CH:2]1[C:11]2[N:10]=[CH:9][C:8]([CH3:12])=[CH:7][C:6]=2[CH2:5][CH2:4][CH2:3]1)=[S:22])[CH3:14]

참가 물질

반응물 2

HCID 2772281Diethyl(2-isothiocyanatoethyl)amine

HCID 123582203-Methyl-5,6,7,8-tetrahydroquinolin-8-amine

생성물 1

HCID 214987878-(2-Diethylaminoethyl)thiocarbamoylamino-3-methyl-5,6,7,8-tetrahydroquinoline

실험 절차

8-amino-3-methyl-5,6,7,8-tetrahydroquinoline may be treated with diethylaminoethyl isothiocyanate according to the procedure of Example 4 to give the title compound.

출처 및 근거

ORD 기록: ord-7c51b101f21642fbb7719120d97cc98f
출처 데이터셋: uspto-grants-1976_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US03991065

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