Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Piperidine → 2-[2-(4-Methyl-1-piperazinyl)-5-thiadiazolyl)-1-methyl-5-nitroimidazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Piperidine | HCID 8082 | — |
| 반응물 | 1-Methylpiperazine | HCID 53167 | — |
| 반응물 | 2-(2-Piperidino-5-thiadiazolyl)-1-methyl-5-nitroimidazole | HCID 21390837 | — |
| 생성물 | 2-[2-(4-Methyl-1-piperazinyl)-5-thiadiazolyl)-1-methyl-5-nitroimidazole | HCID 21390838 | — |
반응 단계
The preparation of the above compound is carried out in the manner described for the 2-piperidino derivative (Example 28), an equivalent of 1-methylpiperazine replacing the piperidine. The crude product is purified by recrystallization from 2-methoxyethanol and melts at 242°-244° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US03991200 |
| 출처 데이터셋 | uspto-grants-1976_11 |
| ORD ID | ord-ddc0afdf3c1241b3bf665258ac784fa3 |
| 출처 메모 | uspto-grants-1976_11 |