HCID 21389207, 화합물 → HCID 178421875, 화합물

반응식

[Br:1][CH:2]1[CH2:10][CH:9]([CH3:11])[CH2:8][C:7]2[C:6](=[NH:12])[NH:5][C:4](=N)[C:3]1=2.Cl.[CH3:15][CH:16]1[N:21]([C:22]2[S:23][CH2:24][C:25](=[NH:27])[N:26]=2)[CH2:20][CH2:19][O:18][CH2:17]1.N=C1C2CCCCC=2C(=N)N1.Cl.N=C1NC(=N)CS1>>[NH:12]=[C:6]1[C:7]2[CH2:8][CH:9]([CH3:11])[CH2:10][CH:2]([Br:1])[C:3]=2[C:4](=[C:24]2[S:23][C:22]([N:21]3[CH2:20][CH2:19][O:18][CH2:17][CH:16]3[CH3:15])=[N:26][C:25]2=[NH:27])[NH:5]1

참가 물질

반응물 4

HCID 21389207HCID 21389207, 화합물

HCID 176526843HCID 176526843, 화합물

HCID 178422102HCID 178422102, 화합물

HCID 178479111HCID 178479111, 화합물

생성물 1

HCID 178421875HCID 178421875, 화합물

실험 절차

Proceeding in a manner similar to that described above in Example 10, part A, but substituting equivalent amounts of 4-bromo-6-methyl-4,5,6,7-tetrahydro-1,3-diiminoisoindoline and 2-(3-methylmorpholino)-4-imino-2-thiazoline hydrochloride for 4,5,6,7-tetrahydro-1,3-diiminoisoindoline and 2,4-diiminothiazolidine hydrochloride respectively, there is obtained as the product 1-imino-4-bromo-6-methyl-4,5,6,7-tetrahydro-3-[2-(3-methylmorpholino)-4-imino-2-thiazolin-5-ylidene]isoindoline.