Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium hydride → 1-Phthalimidopropyl-3-phenyl-5-chloroindazole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | 2-(3-Chloropropyl)-1H-isoindole-1,3(2H)-dione | HCID 245265 | — |
| 반응물 | 5-Chloro-3-phenyl-1H-indazole | HCID 615118 | — |
| 생성물 | 1-Phthalimidopropyl-3-phenyl-5-chloroindazole | HCID 68139474 | 62.2% |
반응 단계
By the procedure similar to that described in Example 24, 3-phenyl-5-chloroindazole (9.2 g), sodium hydride 50% pure (2.3 g) and phthalimidopropyl chloride (9.0 g) were treated to obtain 10.4 g of 1-phthalimidopropyl-3-phenyl-5-chloroindazole. Recrystallization from methanol gave a product having a melting point between 121°-122° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US03994890 |
| 출처 데이터셋 | uspto-grants-1976_11 |
| ORD ID | ord-4a9d886ef31340c58290ae1b777dab7a |
| 출처 메모 | uspto-grants-1976_11 |