Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Formaldehyde → 8-chloro-1-(2-hydroxyethyl)-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Formaldehyde | HCID 712 | — |
| 반응물 | Alprazolam | HCID 2118 | — |
| 생성물 | 8-chloro-1-(2-hydroxyethyl)-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine | HCID 12562508 | — |
반응 단계
heating 8-chloro-6-phenyl-1-methyl-4H-s-triazolo-[4,3-a][1,4]benzodiazepine in an inert organic solvent with paraformaldehyde to 100°-140° C. to give 8-chloro-1-(2-hydroxyethyl)-6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepine; and
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US03994941 |
| 출처 데이터셋 | uspto-grants-1976_11 |
| ORD ID | ord-9a878b20f7c04d5298059dc8e3243778 |
| 출처 메모 | uspto-grants-1976_11 |