Z-Thr(But)-Ser(But)-OMe → H-Thr(But)-Ser(But)-OMe

HRID 1731232노트

반응식

HRID 1731232 반응식
[NH:1](C(OCC1C=CC=CC=1)=O)[C@H:2]([C:10]([NH:12][C@H:13]([C:20]([O:22][CH3:23])=[O:21])[CH2:14][O:15][C:16]([CH3:19])([CH3:18])[CH3:17])=[O:11])[C@@H:3]([CH3:9])[O:4][C:5]([CH3:8])([CH3:7])[CH3:6]>C(OCC)(=O)C.[Pd]>[NH2:1][C@H:2]([C:10]([NH:12][C@H:13]([C:20]([O:22][CH3:23])=[O:21])[CH2:14][O:15][C:16]([CH3:19])([CH3:18])[CH3:17])=[O:11])[C@@H:3]([CH3:9])[O:4][C:5]([CH3:8])([CH3:7])[CH3:6]

참가 물질

4

반응물 1

HCID 131710554Z-Thr(But)-Ser(But)-OMe

생성물 1

HCID 131710555H-Thr(But)-Ser(But)-OMe

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 8857Ethyl Acetate용매

실험 절차

3.27 g of Z-Thr(But)-Ser(But)-OMe in 50 ml of ethyl acetate are hydrogenated in the presence of 0.5 g of palladium on charcoal (10% strength). After the absorption of hydrogen has ceased (1 hour), the catalyst is filtered off and the solution is evaporated. The product, which is obtained as an oil, is a single substance according to thin layer chromatography.

후처리

  1. customAfter the absorption of hydrogen
  2. custom(1 hour)
  3. filtrationthe catalyst is filtered off
  4. customthe solution is evaporated
  5. customThe product, which is obtained as an oil

출처 및 근거

ORD 기록
ord-8d1aeb1e520c44deaaf2c3e697668463
출처 데이터셋
uspto-grants-1976_11
특허 번호
US03994871

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