Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 5-Chloro-1-methyl-1H-pyrazole-4-carboxylic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Ethanol | HCID 702 | — |
| 반응물 | Potassium Hydroxide | HCID 14797 | — |
| 반응물 | Ethyl 5-Chloro-1-methyl-1H-pyrazole-4-carboxylate | HCID 2758821 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 5-Chloro-1-methyl-1H-pyrazole-4-carboxylic acid | HCID 2735774 | — |
반응 단계
5-Chloro-1-methyl-1H-pyrazole-4-carboxylic acid, ethyl ester (13 grams, 0.07 mole) and potassium hydroxide (7.8 grams, 0.14 mole) were combined in 75 ml. of ethanol and refluxed for six hours. The solution was cooled, poured over water, acidified with concentrated hydrochloric acid, and the precipitated solid collected, dried, and recrystallized from water. The resulting 5-chloro-1-methyl-1H-pyrazole-4-carboxylic acid was obtained in the amount of 5.4 grams and melted at 195°-197° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04620865 |
| 출처 데이터셋 | uspto-grants-1986_11 |
| ORD ID | ord-4250428618d14b3b878acef53985b60c |
| 출처 메모 | uspto-grants-1986_11 |