Thiophenol → Ethyl 7-Phenylthio-1H-pyrazolo[4,3-b]pyridine-6-carboxylate

반응식

Cl[C:2]1[C:7]([C:8]([O:10][CH2:11][CH3:12])=[O:9])=[CH:6][N:5]=[C:4]2[CH:13]=[N:14][NH:15][C:3]=12.[C:16]1([SH:22])[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[C:16]1([S:22][C:2]2[C:7]([C:8]([O:10][CH2:11][CH3:12])=[O:9])=[CH:6][N:5]=[C:4]3[CH:13]=[N:14][NH:15][C:3]=23)[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

참가 물질

반응물 2

HCID 7969Thiophenol

HCID 20038759Ethyl 7-chloro-1H-pyrazolo[4,3-B]pyridine-6-carboxylate

생성물 1

HCID 20228771Ethyl 7-Phenylthio-1H-pyrazolo[4,3-b]pyridine-6-carboxylate

실험 절차

The above compound was prepared from ethyl 7-chloro-1H-pyrazolo[4,3-b]pyridine-6-carboxylate and thiophenol in an analogous manner to the preparation of Example 1 giving a white solid, m.p. 130°-131° C.

출처 및 근거

ORD 기록: ord-7f795f88dca24b5e8bc1a3934c836742
출처 데이터셋: uspto-grants-1986_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04621089

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