Thionyl Chloride → 4-(Aminosulfonyl)-3-thiophenecarbonyl chloride

반응식

[NH2:1][S:2]([C:5]1[C:6]([C:10]([OH:12])=O)=[CH:7][S:8][CH:9]=1)(=[O:4])=[O:3].S(Cl)([Cl:15])=O>>[NH2:1][S:2]([C:5]1[C:6]([C:10]([Cl:15])=[O:12])=[CH:7][S:8][CH:9]=1)(=[O:4])=[O:3]

참가 물질

반응물 2

HCID 24386Thionyl Chloride

HCID 30422853-Thiophenecarboxylic acid, 4-(aminosulfonyl)-

생성물 1

HCID 137325564-(Aminosulfonyl)-3-thiophenecarbonyl chloride

반응 조건

온도: 90 °C

실험 절차

A solution of 1.0 g of 4-aminosulfonylthiophene-3-carboxylic acid in 20 ml of thionyl chloride is heated in an oil bath maintained at 90° C. for 2 hours. Rotoevaporation gives 1.0 g of the title compound, m.p. 236°-238° C.

출처 및 근거

ORD 기록: ord-0382d7f24c91420ab51ab823e34230b9
출처 데이터셋: uspto-grants-1986_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US04622402

반응 노트

불러오는 중…